Yoshihiro Shirai Selected Research

pomalidomide

3/2018	Pomalidomide enhanced gemcitabine and nab-paclitaxel on pancreatic cancer both in vitro and in vivo.
3/2018	Pomalidomide promotes chemosensitization of pancreatic cancer by inhibition of NF-κB.

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Yoshihiro Shirai Research Topics

Disease

46	Neoplasms (Cancer) 05/2024 - 09/2014
25	Pancreatic Neoplasms (Pancreatic Cancer) 12/2023 - 01/2016
11	Hepatocellular Carcinoma (Hepatoma) 02/2024 - 01/2018
10	Adenocarcinoma 04/2024 - 09/2015
10	Neoplasm Metastasis (Metastasis) 11/2023 - 09/2014
6	Metabolic Bone Diseases (Osteopenia) 04/2024 - 10/2021
6	Inflammation (Inflammations) 11/2023 - 09/2016
5	Liver Cirrhosis (Hepatic Cirrhosis) 07/2022 - 01/2018
4	Sarcopenia 04/2024 - 03/2022
4	Fibrosis (Cirrhosis) 02/2024 - 01/2021
4	Thrombosis (Thrombus) 04/2023 - 11/2020
4	Pancreatic Fistula (Pancreatic Fistulas) 03/2021 - 01/2015
3	Biliary Tract Neoplasms (Biliary Tract Cancer) 03/2024 - 04/2022
3	Body Weight (Weight, Body) 11/2023 - 01/2017
3	Ascites 05/2023 - 01/2018
3	Cholangiocarcinoma 05/2023 - 01/2018
3	Carcinoma (Carcinomatosis) 04/2022 - 01/2016
2	Hemorrhage 05/2024 - 05/2023
2	Hypertrophy 04/2024 - 12/2021
2	Liver Failure 04/2024 - 01/2018
2	Non-alcoholic Fatty Liver Disease 02/2024 - 09/2022
2	Liver Neoplasms (Liver Cancer) 02/2024 - 11/2020
2	Hepatitis B 05/2023 - 12/2021
2	Cachexia 12/2022 - 09/2022
2	Mitochondrial Diseases (Mitochondrial Disease) 10/2022 - 11/2021
2	Bile Duct Neoplasms (Bile Duct Cancer) 03/2022 - 09/2015
2	Pancreatitis 01/2022 - 06/2015
2	Margins of Excision 11/2021 - 10/2021
2	Colorectal Neoplasms (Colorectal Cancer) 01/2019 - 10/2018
1	Rupture 05/2024
1	Gastroesophageal Reflux (GERD) 04/2024
1	Obesity 04/2024
1	Morbid Obesity 04/2024
1	Stomach Neoplasms (Stomach Cancer) 04/2024
1	Hypoalbuminemia 11/2023
1	Head and Neck Neoplasms (Head and Neck Cancer) 07/2023
1	Pathologic Constriction (Stenosis) 05/2023
1	Hypertension (High Blood Pressure) 05/2023
1	Hydrothorax 05/2023
1	Kidney Diseases (Kidney Disease) 05/2023
1	Acute Cholecystitis 05/2023
1	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 05/2023
1	Polycystic liver disease 05/2023

Drug/Important Bio-Agent (IBA)

11	Indicators and Reagents (Reagents)IBA 01/2024 - 09/2015
9	AlbuminsIBA 01/2024 - 09/2016
8	C-Reactive ProteinIBA 01/2024 - 09/2016
8	nafamostatIBA 01/2022 - 01/2016
7	Gemcitabine FDA Link 01/2022 - 11/2016
4	Amylases FDA Link 02/2024 - 11/2016
4	Biomarkers (Surrogate Marker)IBA 05/2023 - 10/2021
4	Proteins (Proteins, Gene)FDA Link 04/2022 - 12/2021
4	NF-kappa B (NF-kB)IBA 01/2021 - 01/2016
3	Fetal Proteins (Fetoprotein)IBA 02/2024 - 11/2021
3	Hepatitis B Surface Antigens (HBsAg)FDA Link 01/2024 - 12/2022
3	Indocyanine Green (Cardio-Green)FDA LinkGeneric 12/2021 - 01/2018
3	130-nm albumin-bound paclitaxelIBA 10/2020 - 11/2016
3	Serine Proteinase Inhibitors (Serine Protease Inhibitors)IBA 12/2019 - 01/2016
2	alpha-Fetoproteins (alpha-Fetoprotein)IBA 06/2024 - 12/2022
2	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 03/2024 - 04/2022
2	Eicosapentaenoic AcidIBA 03/2024 - 04/2022
2	AntigensIBA 01/2024 - 09/2014
2	CarbohydratesIBA 01/2024 - 09/2014
2	Vitamin K FDA Link 12/2022 - 04/2022
2	AcidsIBA 10/2022 - 06/2021
2	EnzymesIBA 10/2022 - 04/2022
2	Transferrin (beta 2 Transferrin)IBA 12/2021 - 08/2021
2	Cisplatin (Platino)FDA LinkGeneric 12/2021 - 10/2018
2	Small Interfering RNA (siRNA)IBA 11/2021 - 06/2021
2	ThrombomodulinIBA 07/2021 - 01/2017
2	Matrix Metalloproteinases (MMPs)IBA 12/2019 - 10/2018
2	pomalidomideIBA 03/2018 - 03/2018
1	Hemostatics (Antihemorrhagics)IBA 05/2024
1	BilirubinIBA 01/2024
1	Ghrelin ReceptorsIBA 11/2023
1	anamorelinIBA 11/2023
1	Fibrinogen (Factor I)FDA Link 11/2023
1	1-dodecylpyridoxal (PLD)IBA 05/2023

Therapy/Procedure

13	Hepatectomy 04/2024 - 11/2020
13	Pancreaticoduodenectomy 02/2024 - 01/2015
12	Pancreatectomy 04/2024 - 06/2015
11	Drug Therapy (Chemotherapy) 03/2024 - 01/2016
8	Therapeutics 09/2023 - 01/2014
7	Adjuvant Chemotherapy 01/2024 - 04/2022
6	Liver Transplantation 05/2023 - 04/2022
5	Lymph Node Excision (Lymph Node Dissection) 01/2023 - 05/2021
3	Combination Drug Therapy (Combination Chemotherapy) 01/2022 - 03/2018
3	Radiotherapy 01/2021 - 01/2016
2	Transplantation 05/2023 - 04/2023
2	Operative Time 07/2022 - 03/2021
2	Ligation 04/2022 - 12/2021
1	Gastrectomy 04/2024
1	Gastric Bypass (Roux-en-Y Gastric Bypass) 04/2024
1	Fundoplication 04/2024
1	Enteral Nutrition (Feeding, Tube) 03/2024
1	Radiofrequency Ablation 02/2024
1	Traction 11/2023
1	Laparoscopic Cholecystectomy 05/2023
1	Renal Dialysis (Hemodialysis) 05/2023
1	Thoracotomy 05/2023
1	General Anesthesia 05/2023